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Explore a curated collection of research papers, conference summaries, clinical trials, and publications related to Vasculitis (GPA, MPA, and AAV).
The authors conducted a literature search covering publications from January 1998 to September 2022. They selected 15 reported cases of concurrent AAV and systemic TMA. The median patient age was 61 years, and approximately two-thirds were female. MPO‑ANCA positivity was more frequent than PR3‑ANCA positivity.
Most patients achieved hematological remission after treatment.
Kidney involvement varied among patients, with some requiring intensive renal support.
Early recognition of TMA in AAV patients is crucial for effective multidisciplinary management.
This review highlights the complexity of managing AAV when associated with systemic TMA. Clinicians in rheumatology, nephrology, and internal medicine can benefit from understanding these rare but severe presentations to improve outcomes.
Authors:
Indian Journal of Nephrology (2022)
Source / PDF Link:Download PDF – Indian Journal of Nephrology
This retrospective cohort study from central Saudi Arabia investigated the clinical characteristics of Behçet’s Disease — a multisystem form of vasculitis. Conducted at a tertiary care center, the study collected patient demographics, organ involvement, inflammation markers, and treatment responses, detailing the heterogeneous manifestation of the disease in the Saudi population over several years.
This official case report describes a 42‑year‑old male patient diagnosed with Takayasu’s Arteritis, a rare form of large‑vessel vasculitis, at King Faisal Specialist Hospital & Research Center and King Abdulaziz University in Saudi Arabia. The patient had multiple arterial aneurysms, including a significantly enlarged ascending aorta measuring 5.7 cm, which required surgical repair. The report details clinical findings, imaging results, surgical intervention, and successful outcomes, highlighting the disease’s complexity and the importance of specialized cardiac and vascular care.
